Silence Therapeutics plc, a biotechnology company, focuses on the discovery and development of novel ribonucleic acid (RNA) therapeutics in hematology, cardiovascular, and other rare and metabolic indications. The company's platform includes mRNAi GalNAc Oligonucleotide Discovery platform designed to accurately target specific disease-associated genes in the liver. It designs short interfering RNA molecules to harness the body's natural mechanism of RNA interference, and degrading messenger RNA molecules that encode specific targeted disease-associated proteins in a cell. The company is developing various product candidates, including SLN360, which is Phase I clinical trials for the treatment of cardiovascular disease with high lipoprotein; SLN124 that is in Phase I clinical trials for the treatment of non-transfusion dependent thalassemia, and Phase I clinical trials for the treatment of myelodysplastic syndrome; and SLN124 for the treatment of polycythemia vera. It has collaboration agreements with AstraZeneca PLC to discover, develop, and commercialize small interfering RNA therapeutics for the treatment of cardiovascular, renal, metabolic, and respiratory diseases; and Mallinckrodt Pharma IP Trading DAC to develop and commercialize RNAi drug targets designed to silence the complement cascade in complement-mediated disorders. The company also has a collaboration with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three undisclosed targets leveraging Silence's mRNAi GOLD platform. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc is headquartered in London, the United Kingdom.
Employees - 116,
CEO - Mr. Craig A. Tooman M.B.A.,
Sector - Healthcare,
Country - GB,
Market Cap - 129.38M
Altman ZScore(max is 10): -1.47, Piotroski Score(max is 10): 2, Working Capital: $170544000, Total Assets: $202635000, Retained Earnings: $-474044000, EBIT: -35896439, Total Liabilities: $68612000, Revenue: $38473760
- Current Price $2.74 - Analyst Target Price $36.40| Ticker | SLN |
| Index | - |
| Curent Price | 2.74 |
| Change | -5.19% |
| Market Cap | 129.38M |
| Average Volume | 283.94K |
| Income | -75.01M |
| Sales | 20.57M |
| Book Value/Share | 2.69 |
| Cash/Share | 3.66 |
| Dividend Est | - |
| Dividend TTM | - |
| Dividend Ex-Date | - |
| Employees | 116 |
| Moving Avg 20days | -24.89% |
| Moving Avg 50days | -38.29% |
| Moving Avg 200days | -78.00% |
| Shares Outstanding | 47.21M |
| Earnings Date | Feb 27 BMO |
| Inst. Ownership | 32.97% |
| Price/Earnings | - |
| Forwad P/E | - |
| PE Growth | - |
| Price/Sales | 6.29 |
| Price/Book | 1.02 |
| Price/Cash | 0.75 |
| Price/FCF | - |
| Quick Ratio | 9.31 |
| Current Ratio | 9.31 |
| Debt/Equity | 0.00 |
| Return on Assets | -43.26% |
| Return on Equity | -99.23% |
| Return on Investment | -59.17% |
| Gross Margin | 44.54% |
| Ops Margin | -360.59% |
| Profit Margin | -364.60% |
| RSI | 32.98 |
| BETA(β) | 1.25 |
| From 52week Low | 15.61% |
| From 52week High | -88.76% |
| EPS | -1.67 |
| EPS next Year | -0.80 |
| EPS next Qtr | -0.15 |
| EPS this Year | -121.84% |
| EPS next 5 Year | - |
| EPS past 5 Year | 0.35% |
| Sales past 5 Year | 482.00% |
| EPS Y/Y | -16.60% |
| Sales Y/Y | -40.10% |
| EPS Q/Q | -166.56% |
| Sales Q/Q | -58.07% |
| Sales Surprise | 272.19% |
| EPS Surprise | 132.93% |
| ATR(14) | 0.42 |
| Perf Week | -25.75% |
| Perf Month | -42.07% |
| Perf Quarter | -60.17% |
| Perf Year | -87.10% |
| Perf YTD | -60.17% |
| Target Price | 36.40 |
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